Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.50 |
| ▸ | FNTB | P49356 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243932 | 0.81 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL12197936 | 0.80 | PTPN1 (0.73) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL31136174 | 0.79 | PTPN1 (0.56) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL6407780 | 0.76 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL9435685 | 0.76 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL12681232 | 0.76 | SLC1A3 (0.69) | KMT2AALDH1A1POLBNPC1RAB9A | |
| SCHEMBL2098193 | 0.75 | ALDH1A1 (0.59) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL16922181 | 0.75 | NPC1 (0.66) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL2098194 | 0.75 | ALDH1A1 (0.59) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL1503954 | 0.75 | NPC1 (0.66) | KMT2AMEN1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950842-B | Quinoline derivatives having indoleamine-2, 3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-110950842-A | Quinoline derivatives having indoleamine-2, 3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2020-04-03 | — | — | CN | disclosed |