Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243932 | 0.86 | KMT2A (0.59) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL23088339 | 0.83 | KMT2A (0.74) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6408425 | 0.83 | KMT2A (0.57) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6413259 | 0.81 | GAA (0.58) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6414674 | 0.81 | POLB (0.71) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL3986889 | 0.81 | EPHX2 (0.55) | KMT2AMEN1SMN1; SMN2HTTGAA | |
| SCHEMBL6409908 | 0.80 | MEN1 (0.59) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL31590348 | 0.80 | MEN1 (0.59) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL1534196 | 0.79 | TP53 (0.64) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL1504229 | 0.79 | ALDH1A1 (0.68) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138357-B | 2-oxo-1, 2-dihydroquinoline derivative, preparation method and medical application thereof | 天津药物研究院有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113563320-A | Compound containing thiophene structure and application thereof in medicine | 天津药物研究院有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-111138357-A | 2-oxo-1, 2-dihydroquinoline derivative, preparation method and medical application thereof | 天津药物研究院有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-6921770-B2 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-07-26 | — | — | US | disclosed |
| EP-1311160-A4 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INST SCI & TECH (KR) | 2004-04-21 | — | — | EP | disclosed |
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-10-30 | — | — | US | disclosed |
| EP-1311160-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002013611-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | TYR, SYPL1, SSBP1 | KMT2A 2739/4885NPC1 4560/4885RAB9A 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.