Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431589 | 0.88 | EPHX2 (0.68) | PKMEPHX2TP53KMT2ANPC1 | |
| SCHEMBL4112342 | 0.82 | EPHX2 (0.68) | PKMEPHX2KMT2A | |
| SCHEMBL4117411 | 0.79 | EPHX2 (0.64) | EPHX2KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL28430407 | 0.78 | EPHX2 (0.65) | PKMEPHX2KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL30165710 | 0.78 | EPHX2 (0.75) | PKMEPHX2KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL14544649 | 0.78 | LMNA (0.76) | PKMTP53KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL14521774 | 0.77 | PKM (0.72) | PKMTP53KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28430443 | 0.76 | EPHX2 (0.68) | PKMEPHX2TP53KMT2ASMN1; SMN2 | |
| SCHEMBL653169 | 0.75 | EPHX1 (1.00) | EPHX2KMT2ANPC1SMN1; SMN2EPHX1 | |
| SCHEMBL6439308 | 0.75 | KMT2A (1.00) | PKMEPHX2TP53KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423396-A | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | claimed |
| CN-111423396-A | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | disclosed |