Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284108 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1SLC6A3L3MBTL1 | |
| SCHEMBL298303 | 0.81 | MBOAT4 (0.47) | ALDH1A1HTTTDP1MAPK1L3MBTL1 | |
| SCHEMBL13570637 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1HTTTDP1MAPK1SLC6A3 | |
| SCHEMBL8015922 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1HTTTDP1MAPK1SLC6A3 | |
| SCHEMBL5206425 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTTTDP1MAPK1SLC6A3 | |
| SCHEMBL5436754 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1SLC6A3L3MBTL1 | |
| SCHEMBL27407597 | 0.79 | HTT (0.43) | ALDH1A1HTTTDP1MAPK1SLC6A3 | |
| Cyclopropane SCHEMBL5689141 | 0.77 | SMN1; SMN2 (0.45) | ALDH1A1HTTTDP1MAPK1SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL27875656 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPK1SLC6A3L3MBTL1 | |
| SCHEMBL19690610 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HTTTDP1MAPK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428503-B1 | Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces | Justus Liebig Universität Giessen (DE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2012032085-A1 | SYNTHESIS OF TRIVALENT FLEXIBLE FRAMEWORKS WITH LIGANDS COMPRISING CATECHOL UNITS FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2428503-A1 | Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |