Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13570637 | 0.96 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1AHTTALDH1A1KMT2A | |
| SCHEMBL8015922 | 0.96 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1AHTTALDH1A1KMT2A | |
| SCHEMBL27711516 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 | |
| SCHEMBL27583508 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 | |
| SCHEMBL9629603 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 | |
| SCHEMBL27685711 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 | |
| SCHEMBL27970687 | 0.82 | THRA (0.46) | FFAR1FFAR4GRM2GRM3 | |
| SCHEMBL7440964 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 | |
| SCHEMBL28362146 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 | |
| SCHEMBL28366123 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2HIF1AALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648924-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | The Nottingham Trent University (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2004113363-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | THE NOTTINGHAM TRENT UNIVERSITY (GB) | 2004-12-29 | — | — | WO | disclosed |