Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747889 | 0.71 | AKR1C3 (0.44) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL9475462 | 0.65 | AKR1C3 (0.63) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL3956232 | 0.65 | AKR1C3 (0.81) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL3843558 | 0.65 | AKR1C3 (0.81) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL28381581 | 0.63 | AKR1C3 (0.41) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL27410699 | 0.63 | NPC1 (0.65) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL21629505 | 0.62 | HPGD (0.61) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL10414512 | 0.62 | AKR1C3 (0.54) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL3677894 | 0.62 | AKR1C3 (0.69) | AKR1C3MAPTHTTMAPK1NPC1 | |
| SCHEMBL10395918 | 0.61 | LMNA (0.60) | AKR1C3MAPTHTTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196770-B | Simple preparation method of bromfenac sodium | 新发药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-110885296-B | Preparation method of bromfenac sodium | 新发药业有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-111196770-A | Simple preparation method of bromfenac sodium | 新发药业有限公司 | 2020-05-26 | — | — | CN | disclosed |