Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18298125 | 0.88 | HTT (0.38) | HTTNPC1CA1CA2KMT2A | |
| SCHEMBL28422972 | 0.86 | HTT (0.36) | HTTNPC1CA1CA2KMT2A | |
| SCHEMBL18298130 | 0.86 | MET (0.34) | HTTNPC1KMT2AMEN1MAPT | |
| SCHEMBL28420796 | 0.83 | LGALS3 (0.38) | ALDH1A1MAPTKDM4EPTPN1CYP2C19 | |
| SCHEMBL28426427 | 0.80 | NPC1 (0.40) | HTTNPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL28424690 | 0.76 | NPC1 (0.34) | NPC1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL20557379 | 0.75 | HTT (0.38) | HTTNPC1CA1CA2KMT2A | |
| SCHEMBL18298135 | 0.75 | LGALS3 (0.39) | HTTNPC1CA1CA2KMT2A | |
| SCHEMBL15481902 | 0.73 | ESR2 (0.40) | NPC1CA1CA2ALDH1A1MAPT | |
| SCHEMBL28428520 | 0.73 | LGALS3 (0.36) | NPC1KMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011168-B | Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides | 富士胶片株式会社 | 2020-06-09 | — | — | CN | disclosed |