Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425924 | 0.87 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28709000 | 0.85 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28420705 | 0.85 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL18298130 | 0.83 | MET (0.34) | NPC1RAB9AMAPTKMT2APOLB | |
| SCHEMBL28719560 | 0.82 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL18298145 | 0.81 | FLT1 (0.36) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28424714 | 0.80 | HTT (0.37) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28420796 | 0.80 | LGALS3 (0.38) | MAPTALDH1A1HPGD | |
| SCHEMBL20141708 | 0.78 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL25400709 | 0.75 | NPC1 (0.42) | NPC1RAB9AMAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011168-B | Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides | 富士胶片株式会社 | 2020-06-09 | — | — | CN | disclosed |