Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17153769 | 0.79 | ESR1 (0.57) | ESR1SMN1; SMN2EGLN3MAPTFPR2 | |
| SCHEMBL992745 | 0.79 | SMN1; SMN2 (0.61) | ESR1SMN1; SMN2MAPTMAPK1POLB | |
| SCHEMBL7391278 | 0.79 | ARG1 (0.58) | ESR1SMN1; SMN2EGLN3MAPTFPR2 | |
| SCHEMBL4239946 | 0.77 | ESR1 (0.54) | ESR1SMN1; SMN2EGLN3MAPTFPR2 | |
| SCHEMBL27886864 | 0.77 | SMN1; SMN2 (0.58) | ESR1SMN1; SMN2EGLN3MAPTFPR2 | |
| SCHEMBL28422751 | 0.76 | FPR2 (0.48) | ESR1SMN1; SMN2FPR2 | |
| SCHEMBL28640086 | 0.75 | — | — | |
| SCHEMBL2627813 | 0.75 | SMN1; SMN2 (0.97) | ESR1SMN1; SMN2EGLN3MAPTFPR2 | |
| SCHEMBL30775444 | 0.74 | ESR1 (1.00) | ESR1SMN1; SMN2EGLN3MAPK1TBXAS1 | |
| SCHEMBL16319226 | 0.74 | CA12 (0.54) | ESR1SMN1; SMN2EGLN3KMOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356680-A | Selective inhibitors of NLRP3inflammasome | 诺瑟拉有限公司 | 2020-06-30 | — | — | CN | disclosed |