Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360233 | 0.84 | KMT2A (0.64) | KMT2ATP53MEN1CKS1BSKP2 | |
| SCHEMBL29862447 | 0.84 | KMT2A (0.64) | KMT2ATP53MEN1CKS1BSKP2 | |
| SCHEMBL28424154 | 0.83 | TOP2A (0.49) | KMT2ATP53MEN1TOP2AHPGD | |
| SCHEMBL28421262 | 0.83 | SLC40A1 (0.50) | KMT2AMEN1SLC40A1TOP2AHPGD | |
| SCHEMBL16887761 | 0.81 | HTT (0.61) | KMT2AMEN1TOP2AHPGDMAPT | |
| SCHEMBL9367514 | 0.78 | KMT2A (0.57) | KMT2ATP53MEN1CKS1BSKP2 | |
| SCHEMBL28416081 | 0.78 | SLC40A1 (0.52) | KMT2ATP53MEN1CKS1BSKP2 | |
| SCHEMBL23360257 | 0.78 | KMT2A (0.74) | KMT2ATP53MEN1CKS1BSKP2 | |
| SCHEMBL29862819 | 0.78 | KMT2A (0.74) | KMT2ATP53MEN1CKS1BSKP2 | |
| SCHEMBL8102961 | 0.77 | TDP1 (0.66) | KMT2ATP53MEN1SLC40A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320579-B | Preparation method of 8-amide-5-halogenated quinoline derivative | 常州工程职业技术学院 | 2021-06-29 | — | — | CN | disclosed |
| CN-111320579-A | Preparation method of 8-amide-5-halogenated quinoline derivative | 常州工程职业技术学院 | 2020-06-23 | — | — | CN | disclosed |