Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431943 | 0.90 | PDE1B (0.49) | PDE1BRAB9ACNR1CNR2PDE5A | |
| SCHEMBL28428236 | 0.89 | PDE1B (0.47) | PDE1BRAB9ACNR1CNR2PDE5A | |
| SCHEMBL1592875 | 0.83 | NR3C1 (0.45) | RAB9ACNR1CNR2MEN1KMT2A | |
| SCHEMBL24566406 | 0.82 | CNR1 (0.50) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL28431878 | 0.82 | CNR1 (0.47) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL1592906 | 0.80 | PDE1B (0.55) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL1593023 | 0.80 | CNR1 (0.47) | PDE1BCNR1CNR2PDE5AMEN1 | |
| SCHEMBL28432732 | 0.79 | PDE5A (0.38) | PDE1BRAB9APDE5AMEN1KMT2A | |
| SCHEMBL1593855 | 0.79 | PTGDR2 (0.44) | PDE1BCNR1CNR2MEN1KMT2A | |
| SCHEMBL1592988 | 0.76 | MEN1 (0.47) | PDE1BCNR1CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393433-B | Heterocyclic benzene sulfonamide compound and application thereof | 暨南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-111393433-A | Heterocyclic benzene sulfonamide compound and application thereof | 暨南大学 | 2020-07-10 | — | — | CN | disclosed |