Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425625 | 0.89 | PDE1B (0.48) | PDE1BALDH1A1CA1CA2ALOX15 | |
| SCHEMBL28431943 | 0.88 | PDE1B (0.49) | PDE1BALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL1592875 | 0.81 | NR3C1 (0.45) | ALDH1A1MAPTALOX15KDM4ENPC1 | |
| SCHEMBL24566406 | 0.81 | CNR1 (0.50) | PDE1BALDH1A1MAPTALOX15LMNA | |
| SCHEMBL1593023 | 0.81 | CNR1 (0.47) | PDE1BALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL1592906 | 0.78 | PDE1B (0.55) | PDE1BALDH1A1MAPTALOX15LMNA | |
| SCHEMBL28431878 | 0.78 | CNR1 (0.47) | PDE1BALDH1A1MAPTALOX15LMNA | |
| SCHEMBL1593855 | 0.77 | PTGDR2 (0.44) | PDE1BALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1594020 | 0.76 | CNR1 (0.46) | PDE1BALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL28432732 | 0.75 | PDE5A (0.38) | PDE1BALDH1A1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393433-B | Heterocyclic benzene sulfonamide compound and application thereof | 暨南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-111393433-A | Heterocyclic benzene sulfonamide compound and application thereof | 暨南大学 | 2020-07-10 | — | — | CN | disclosed |