Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423672 | 0.90 | PTPN2 (0.53) | PTPN2PTPN1PTPN6KDM4EPKM | |
| SCHEMBL19173097 | 0.83 | NAMPT (0.51) | PTPN2PTPN1PTPN6KDM4EPKM | |
| SCHEMBL65285 | 0.81 | GPR119 (0.59) | KDM4EPKMKMT2AGPR119 | |
| SCHEMBL17202799 | 0.80 | EPHX2 (0.48) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL19173146 | 0.79 | GPR119 (0.53) | PTPN2PTPN1PTPN6BCHEMAOB | |
| SCHEMBL6227709 | 0.79 | PTPN2 (0.50) | PTPN2PTPN1PTPN6KDM4EPKM | |
| SCHEMBL4010884 | 0.79 | CA12 (0.69) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL17832684 | 0.78 | ALDH1A1 (0.73) | PTPN2PTPN1PTPN6KDM4EPKM | |
| SCHEMBL1252952 | 0.78 | KDM4E (0.57) | KDM4EPKMKMT2AGPR119MAPT | |
| SCHEMBL6205109 | 0.77 | KDM4E (0.52) | KDM4EPKMGPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423434-A | Carbonamide derivative and preparation method thereof | 四川海思科制药有限公司 | 2020-07-17 | — | — | CN | disclosed |