Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.56 |
| ▸ | CTSS | P25774 | 11/20 | 0.50 |
| ▸ | CTSB | P07858 | 9/20 | 0.50 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693609 | 0.84 | CTSL (0.56) | CTSLCTSSCTSBCTSK | |
| SCHEMBL28421665 | 0.84 | CTSL (0.74) | CTSLCTSSCTSBCTSK | |
| SCHEMBL28424711 | 0.84 | CTSL (0.74) | CTSLCTSSCTSBCTSK | |
| SCHEMBL23673493 | 0.82 | CTSB (0.57) | CTSLCTSSCTSBCTSK | |
| SCHEMBL20335396 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSKTSHR | |
| SCHEMBL20335433 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSKTSHR | |
| SCHEMBL23693620 | 0.80 | CTSB (0.54) | CTSLCTSSCTSBCTSKPOLB | |
| SCHEMBL23693158 | 0.79 | POLB (0.42) | CTSLCTSSCTSBCTSKPOLB | |
| SCHEMBL23693285 | 0.79 | CTSL (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL28649694 | 0.79 | CTSL (0.52) | CTSLCTSSCTSBCTSKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |