Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719560 | 0.91 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28426427 | 0.87 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28709000 | 0.86 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28420705 | 0.86 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28428520 | 0.82 | LGALS3 (0.36) | NPC1RAB9AMAPTKMT2APOLB | |
| SCHEMBL16774479 | 0.81 | LGALS3 (0.37) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL18298125 | 0.80 | HTT (0.38) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL28428818 | 0.80 | LGALS3 (0.40) | NPC1RAB9AMAPTLMNALGALS3 | |
| SCHEMBL28716111 | 0.76 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28562523 | 0.76 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011168-B | Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides | 富士胶片株式会社 | 2020-06-09 | — | — | CN | disclosed |