Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420705 | 1.00 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAABCB1 | |
| SCHEMBL28627968 | 0.91 | TSHR (0.39) | LMNAABCB1KMT2APOLBTSHR | |
| SCHEMBL28719560 | 0.86 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28425924 | 0.86 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28426427 | 0.85 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28423026 | 0.83 | MET (0.36) | NPC1RAB9AMAPTKMT2APOLB | |
| SCHEMBL28426565 | 0.81 | LGALS3 (0.34) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL28422972 | 0.81 | HTT (0.36) | NPC1MAPTKMT2APOLB | |
| SCHEMBL28427485 | 0.81 | KDM4E (0.39) | MAPT | |
| SCHEMBL28400811 | 0.77 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137641-B | Cyclic dinucleotide compounds as sting agonists | 默沙东公司 | 2022-04-01 | — | — | CN | disclosed |