Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646047 | 0.77 | PDGFRA (0.42) | SIGMAR1SMN1; SMN2HTTRECQLCA1 | |
| SCHEMBL29111064 | 0.77 | PDGFRA (0.42) | SIGMAR1SMN1; SMN2HTTRECQLCA1 | |
| SCHEMBL29111047 | 0.73 | MEN1 (0.44) | HTTALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL30646027 | 0.73 | MEN1 (0.44) | HTTALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL27935616 | 0.70 | SIGMAR1 (0.67) | SIGMAR1SMN1; SMN2HTTRECQLF2 | |
| SCHEMBL27950117 | 0.66 | SIGMAR1 (0.62) | SIGMAR1SMN1; SMN2HTTRECQLALDH1A1 | |
| SCHEMBL1674342 | 0.66 | SIGMAR1 (0.73) | SIGMAR1SMN1; SMN2F2ALDH1A1 | |
| SCHEMBL30646062 | 0.65 | EGFR (0.44) | — | |
| SCHEMBL27935609 | 0.64 | SIGMAR1 (0.70) | SIGMAR1RECQLF2ALDH1A1MAPT | |
| SCHEMBL2566683 | 0.63 | SIGMAR1 (0.78) | SIGMAR1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |