Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 12/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646047 | 1.00 | PDGFRA (0.42) | PDGFRAKDRHTTRECQLSMN1; SMN2 | |
| SCHEMBL30646062 | 0.89 | EGFR (0.44) | EGFRKIT | |
| SCHEMBL28428993 | 0.86 | EGFR (0.41) | EGFRKIT | |
| SCHEMBL28423107 | 0.86 | KDR (0.45) | PDGFRAKDRACHEBACE1EGFR | |
| SCHEMBL30646060 | 0.86 | KDR (0.45) | PDGFRAKDRACHEBACE1EGFR | |
| SCHEMBL29111046 | 0.84 | PDGFRA (0.43) | PDGFRAKDRACHEBACE1EGFR | |
| SCHEMBL28423290 | 0.83 | EGFR (0.43) | EGFR | |
| SCHEMBL30646063 | 0.83 | EGFR (0.43) | EGFR | |
| SCHEMBL28426760 | 0.77 | SIGMAR1 (0.43) | HTTRECQLSMN1; SMN2SIGMAR1CA1 | |
| SCHEMBL29111055 | 0.76 | PDGFRA (0.48) | PDGFRAKDRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |