Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.52 |
| ▸ | FLT3 | P36888 | 4/20 | 0.52 |
| ▸ | CSF1R | P07333 | 3/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.52 |
| ▸ | KIT | P10721 | 6/20 | 0.51 |
| ▸ | FLT4 | P35916 | 2/20 | 0.51 |
| ▸ | MET | P08581 | 5/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.49 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | TEK | Q02763 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420947 | 0.88 | KDR (0.51) | KDRFLT3CSF1RPDGFRBPDGFRA | |
| SCHEMBL28428906 | 0.84 | PDE4A (0.49) | KDRFLT3CSF1RPDGFRBPDGFRA | |
| SCHEMBL30646026 | 0.81 | PDGFRA (0.62) | KDRPDGFRBPDGFRAKITMET | |
| SCHEMBL29111060 | 0.81 | PDGFRA (0.62) | KDRPDGFRBPDGFRAKITMET | |
| SCHEMBL28428907 | 0.80 | PDGFRA (0.55) | KDRFLT3CSF1RPDGFRBPDGFRA | |
| SCHEMBL28893679 | 0.79 | MET (0.64) | KDRFLT3CSF1RPDGFRBPDGFRA | |
| SCHEMBL28426786 | 0.79 | SRC (0.57) | KDRPDGFRAKITMETAURKB | |
| Hydrochloric Acid SCHEMBL23359655 | 0.79 | KRAS (0.55) | PDGFRBPDGFRAKITFGFR2 | |
| SCHEMBL2172904 | 0.78 | PDGFRA (0.64) | KDRFLT3CSF1RPDGFRBPDGFRA | |
| SCHEMBL19957113 | 0.78 | KDR (0.63) | KDRFLT3CSF1RPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |