SCHEMBL28427477

SCHEMBL28427477

C[Si](C)(C)CCC(=O)Nc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 9/20 0.64
HDAC1 Q13547 9/20 0.64
HDAC11 Q96DB2 9/20 0.64
HDAC8 Q9BY41 9/20 0.64
HDAC6 Q9UBN7 9/20 0.64
HDAC5 Q9UQL6 9/20 0.64
HDAC3 O15379 8/20 0.64
HDAC2 Q92769 8/20 0.64
HDAC10 Q969S8 8/20 0.64
MAPT P10636 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
HTT P42858 1/20 0.58
ALDH1A1 P00352 1/20 0.57
HPGD P15428 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HDAC7 Q8WUI4 8/20 0.56
HDAC9 Q9UKV0 8/20 0.56
CYP3A4 P08684 2/20 0.54
KDM4E B2RXH2 1/20 0.54
BRD4 O60885 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11203580 0.89 HDAC4 (0.69) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL1948543 0.82 HDAC3 (0.44) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL3342586 0.82 L3MBTL1 (0.80) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL11016834 0.81 EPHX2 (0.55) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL9888 0.79 ALDH1A1 (0.86) HDAC1HDAC3HDAC2MAPTL3MBTL1
SCHEMBL12535778 0.78 MEN1 (0.68) MAPTALDH1A1HPGDKDM4E
SCHEMBL11203826 0.78 HDAC1 (0.64) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL5805500 0.78 HDAC4 (1.00) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL517309 0.78 HDAC4 (0.81) HDAC4HDAC1HDAC11HDAC8HDAC6
SCHEMBL6296181 0.78 HDAC4 (0.75) HDAC4HDAC1HDAC11HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115556446-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
CN-115556441-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
CN-111386185-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2020-07-07 CN disclosed