Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215127 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL10964124 | 0.84 | ALDH1A1 (0.67) | TDP1ALDH1A1L3MBTL1SMN1; SMN2NCOA1 | |
| Hydrochloric Acid SCHEMBL11587322 | 0.83 | TDP1 (0.55) | TDP1ALDH1A1L3MBTL1SMN1; SMN2NCOA1 | |
| SCHEMBL589908 | 0.81 | ALDH1A1 (0.61) | TDP1ALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL29603881 | 0.80 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL1161927 | 0.80 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL10531193 | 0.79 | TSHR (0.65) | TDP1ALDH1A1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL9747334 | 0.78 | MAPT (0.48) | TDP1ALDH1A1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL28307481 | 0.78 | ALDH1A1 (0.58) | TDP1ALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL57166 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1TSHRSMN1; SMN2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069845-B | One-step preparation method of bromo-1, 4-naphthoquinone | 大连理工大学 | 2020-04-14 | — | — | CN | disclosed |