SCHEMBL589908

SCHEMBL589908

COc1ccc([N+](=O)[O-])c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
TDP1 Q9NUW8 3/20 0.61
CTSB P07858 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
IDO1 P14902 1/20 0.48
EP300 Q09472 1/20 0.47
KAT8 Q9H7Z6 1/20 0.47
CYP19A1 P11511 1/20 0.47
AR P10275 1/20 0.46
LMNA P02545 1/20 0.45
MAPK1 P28482 3/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
IMPDH2 P12268 1/20 0.44
IMPDH1 P20839 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
AKR1C4 P17516 1/20 0.44
AKR1C3 P42330 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10964124 0.89 ALDH1A1 (0.67) ALDH1A1TDP1CTSBL3MBTL1AR
SCHEMBL9468792 0.85 ALDH1A1 (0.46) ALDH1A1TDP1CTSBL3MBTL1GAA
SCHEMBL9468793 0.85 ALDH1A1 (0.46) ALDH1A1TDP1CTSBL3MBTL1LMNA
SCHEMBL28307481 0.82 ALDH1A1 (0.58) ALDH1A1TDP1CTSBL3MBTL1CYP19A1
SCHEMBL7788656 0.82 TDP1 (0.80) ALDH1A1TDP1CTSBARLMNA
SCHEMBL28428409 0.81 TDP1 (0.60) ALDH1A1TDP1CTSBL3MBTL1CYP19A1
SCHEMBL7705373 0.81 ALDH1A1 (0.58) ALDH1A1TDP1CTSBL3MBTL1AR
SCHEMBL29079739 0.80 PDGFRA (0.56)
SCHEMBL27740333 0.80 ALDH1A1 (0.54) ALDH1A1TDP1CTSBARLMNA
SCHEMBL8321793 0.79 TDP1 (0.52) ALDH1A1TDP1CTSBARCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
CN-114773201-A Method for rapidly preparing 1-methoxy-4-nitronaphthalene based on micro-channel continuous flow technology 都创(上海)医药开发有限公司 2022-07-22 CN claimed
CN-110590558-A Method for catalyzing selective nitration of 1-methoxynaphthalene by using zeolite molecular sieve 蚌埠学院 2019-12-20 CN claimed
EP-2486115-B1 ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF FRAUNHOFER GES FORSCHUNG (DE) 2015-05-20 EP claimed
EP-2486115-A1 ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF Fraunhofer Gesellschaft zur Förderung der angewandten Wissenschaft E.V. (DE) 2012-08-15 EP claimed
WO-2011042117-A1 ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2011-04-14 WO claimed
EP-1037873-B1 METHOD FOR PRODUCING ORGANIC HYDROXYLAMINES CONSORTIUM ELEKTROCHEM IND (DE) 2001-08-22 EP claimed
US-6211410-B1 PARTIALLY HYDROGENATING ORGANIC NITRO COMPOUND IN PRESENCE OF ORGANIC BASE OR AMMONIA, TRIVALENT PHOSPHORUS COMPOUND AND HYDROGENATION CATALYST Consortium für elektrochemische Industrie GmbH (DE) 2001-04-03 US claimed
EP-1037873-A1 METHOD FOR PRODUCING ORGANIC HYDROXYLAMINES Consortium für elektrochemische Industrie GmbH (DE) 2000-09-27 EP claimed
WO-1999028289-A1 METHOD FOR PRODUCING ORGANIC HYDROXYLAMINES Consortium für elektrochemische Industrie GmbH (DE) 1999-06-10 WO claimed
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US disclosed
CN-116535340-A Substituted N-aryl-1-naphthylamine compound, preparation method and pharmaceutical application thereof 中国医学科学院药物研究所 2023-08-04 CN disclosed
US-11712680-B2 Process for reducing aromatic nitro compounds with supported catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-08-01 US disclosed
EP-4208021-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS Bio-Rad Laboratories, Inc. (US) 2023-07-12 EP disclosed
CN-116097093-A Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers 生物辐射实验室股份有限公司 2023-05-09 CN disclosed
WO-1992014697-A1 SUBSTITUTED GUANIDINES AND DERIVATIVES THEREOF AS MODULATORS OF NEUROTRANSMITTER RELEASE AND NOVEL METHODOLOGY FOR IDENTIFYING NEUROTRANSMITTER RELEASE BLOCKERS CAMBRIDGE NEUROSCIENCE, INC. (US) 1992-09-03 WO disclosed
US-4962198-A Process for the hydroxylation of electrophilic aromatic compounds BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US disclosed
US-4960950-A Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1990-10-02 US disclosed
EP-0352563-A2 Process for the hydroxylation of electrophilic aromatic compounds BAYER AG (DE) 1990-01-31 EP disclosed
EP-0335274-A2 Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1989-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11712680-B2 Process for reducing aromatic nitro compounds with supported catalyst ARG2, NDUFS5, NDUFS7 ALDH1A1 2712/4885TDP1 2491/4885CTSB 3238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.