Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11164993 | 0.84 | TSHR (0.75) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL21836147 | 0.82 | ALDH1A1 (0.62) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL1929898 | 0.81 | TSHR (0.71) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL4438514 | 0.81 | TSHR (0.71) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL1366420 | 0.81 | TSHR (0.80) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL8811649 | 0.80 | TSHR (0.70) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL4349174 | 0.80 | TSHR (0.70) | CA1CA2TSHRTP53ALDH1A1 | |
| SCHEMBL27555709 | 0.80 | TSHR (0.70) | CA1CA2TSHRTP53ALDH1A1 | |
| SCHEMBL63466 | 0.80 | TSHR (0.70) | CA1CA2TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL18394717 | 0.80 | TSHR (0.70) | CA1CA2TSHRTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920495-A | Mining grouting reinforcement filling agent and preparation method thereof | 煤炭科学技术研究院有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114773565-A | Flame-retardant thermoplastic polyurethane resin, preparation method and application thereof, and protective clothing | 安丹达工业技术(上海)有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114369319-A | Dummy skin and preparation method thereof | 北京可维汇众科技发展有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-111004366-A | Tissue organ-imitated polyurethane-based composite material for dummy and preparation method thereof | 湖南大学 | 2020-04-14 | — | — | CN | claimed |
| CN-114773565-B | Flame-retardant thermoplastic polyurethane resin, preparation method thereof, application thereof and protective clothing | 安丹达工业技术(上海)有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-114920495-A | Mining grouting reinforcement filling agent and preparation method thereof | 煤炭科学技术研究院有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114773565-A | Flame-retardant thermoplastic polyurethane resin, preparation method and application thereof, and protective clothing | 安丹达工业技术(上海)有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114369319-A | Dummy skin and preparation method thereof | 北京可维汇众科技发展有限公司 | 2022-04-19 | — | — | CN | disclosed |