Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001647 | 0.82 | CYP1A2 (0.56) | CYP1A2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL283861 | 0.81 | MEN1 (0.42) | MEN1KMT2ASCN9A | |
| SCHEMBL2210778 | 0.81 | CYP1A2 (0.54) | CYP1A2ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL2001591 | 0.80 | ALDH1A1 (0.65) | CYP1A2ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL1208379 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28428697 | 0.80 | TSHR (0.64) | CYP1A2ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL263895 | 0.79 | MGAM (0.51) | MEN1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL28434347 | 0.79 | KDM4E (0.65) | CYP1A2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28231530 | 0.78 | ALDH1A1 (0.48) | CYP1A2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL269263 | 0.78 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | claimed |
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |