Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847484 | 0.93 | L3MBTL1 (0.59) | TSHRL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL2846692 | 0.93 | L3MBTL1 (0.62) | TSHRL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL2842908 | 0.89 | TSHR (0.75) | TSHRALDH1A1GAATP53 | |
| SCHEMBL2846591 | 0.89 | L3MBTL1 (0.66) | TSHRL3MBTL1ALDH1A1GAA | |
| SCHEMBL2841062 | 0.89 | L3MBTL1 (0.66) | TSHRL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL2842383 | 0.89 | L3MBTL1 (0.56) | TSHRL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL2843771 | 0.88 | ALDH1A1 (0.62) | TSHRL3MBTL1ALDH1A1GAATP53 | |
| SCHEMBL2843212 | 0.88 | TSHR (0.64) | TSHRL3MBTL1GAATP53 | |
| SCHEMBL2843205 | 0.88 | MAPT (0.55) | TSHRL3MBTL1ALDH1A1GAATP53 | |
| SCHEMBL2841026 | 0.88 | ALDH1A1 (0.62) | TSHRL3MBTL1ALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | claimed |
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |