Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGAV | P06756 | 4/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743093 | 0.82 | IRAK4 (0.53) | SMN1; SMN2HTTNPC1RAB9AITGB3 | |
| SCHEMBL20743189 | 0.82 | NPC1 (0.48) | SMN1; SMN2HTTNPC1RAB9AITGB3 | |
| SCHEMBL30645121 | 0.82 | NPC1 (0.48) | SMN1; SMN2HTTNPC1RAB9AITGB3 | |
| SCHEMBL30645027 | 0.82 | IRAK4 (0.53) | SMN1; SMN2HTTNPC1RAB9AITGB3 | |
| SCHEMBL20743761 | 0.82 | NPC1 (0.47) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL30645019 | 0.82 | NPC1 (0.47) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL20743099 | 0.82 | RAB9A (0.48) | SMN1; SMN2HTTNPC1RAB9AAKR1C3 | |
| SCHEMBL20743140 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL30645024 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL20743025 | 0.80 | MTOR (0.49) | SMN1; SMN2HTTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | claimed |
| CN-111344281-A | Potassium channel inhibitors of substituted benzimidazoles | 阿塞西翁制药公司 | 2020-06-26 | — | — | CN | claimed |
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111344281-A | Potassium channel inhibitors of substituted benzimidazoles | 阿塞西翁制药公司 | 2020-06-26 | — | — | CN | disclosed |