Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420857 | 0.88 | TDP1 (0.57) | MAPTLMNANPSR1HPGDGLP1R | |
| SCHEMBL28422024 | 0.85 | MAPT (0.49) | MAPTLMNANPSR1HPGDALDH1A1 | |
| SCHEMBL28422077 | 0.80 | ALOX12 (0.64) | MAPTLMNANPSR1HPGDGLP1R | |
| SCHEMBL29889924 | 0.79 | PKM (0.46) | MAPTLMNANPSR1HPGDALDH1A1 | |
| SCHEMBL28427552 | 0.78 | TARBP2 (0.46) | MAPTLMNANPSR1ALDH1A1TDP1 | |
| SCHEMBL2019580 | 0.77 | MAPT (0.49) | MAPTNPSR1HPGDGLP1RALDH1A1 | |
| SCHEMBL28423614 | 0.75 | ALOX12 (0.48) | MAPTLMNANPSR1ALDH1A1TDP1 | |
| SCHEMBL11254260 | 0.74 | HSD17B10 (0.49) | MAPTLMNAHPGDALDH1A1KDM4E | |
| SCHEMBL21296944 | 0.74 | MAPT (0.56) | MAPTLMNANPSR1HPGDALDH1A1 | |
| SCHEMBL29799115 | 0.74 | MAPT (0.56) | MAPTLMNANPSR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981819-B | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110981819-A | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2020-04-10 | — | — | CN | disclosed |