Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987398 | 0.86 | CA2 (0.46) | CA2MAPK1FOLH1CHRM1AKR1A1 | |
| SCHEMBL11087832 | 0.84 | CA2 (0.47) | CA2MAPK1FOLH1CHRM1AKR1A1 | |
| SCHEMBL110312 | 0.82 | SLC1A2 (0.42) | CA2MAPK1FOLH1TDP1AKR1B1 | |
| SCHEMBL28429252 | 0.81 | DGKA (0.45) | PLA2G4BTDP1AKR1B1MAPTKMT2A | |
| SCHEMBL6425935 | 0.79 | AKR1B1 (0.48) | TDP1AKR1B1MAPTKMT2AFFAR4 | |
| SCHEMBL9171651 | 0.77 | FFAR4 (0.57) | PLA2G4BTDP1AKR1B1PLA2G2CMAPT | |
| SCHEMBL18812872 | 0.76 | EPHX2 (0.36) | PLA2G4BTDP1AKR1B1PLA2G2CMAPT | |
| SCHEMBL3346534 | 0.76 | CHRM1 (0.52) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL1551902 | 0.75 | CA2 (0.65) | CA2MAPK1FOLH1CHRM1AKR1A1 | |
| SCHEMBL5569740 | 0.75 | ALDH1A1 (0.47) | FOLH1EPHX2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459514-B | Tread rubber composition and pneumatic tire | 住友橡胶工业株式会社 | 2020-07-03 | — | — | CN | disclosed |