Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684411 | 0.81 | ALDH1A1 (0.48) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL30468473 | 0.81 | CYP1A2 (0.45) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL3379806 | 0.81 | CYP1A2 (0.45) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL14744170 | 0.80 | CYP1A2 (0.47) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL28151333 | 0.80 | CYP1A2 (0.44) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL30206593 | 0.80 | CYP1A2 (0.47) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL4943689 | 0.80 | CYP1A2 (0.60) | KCNJ1CYP1A2ALDH1A1TDP1TSHR | |
| SCHEMBL1464650 | 0.80 | LOXL2 (0.50) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL28445856 | 0.79 | CYP3A4 (0.53) | KCNJ1CYP1A2POLBALDH1A1TDP1 | |
| SCHEMBL28756816 | 0.79 | ALDH1A1 (0.50) | KCNJ1CYP1A2ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356687-B | Pyrimidine-containing tri-substituted imidazole compound and application thereof | 广州必贝特医药技术有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-111566100-A | Pyrimidine compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-111356687-A | Pyrimidine-containing tri-substituted imidazole compound and application thereof | 广州必贝特医药技术有限公司 | 2020-06-30 | — | — | CN | disclosed |