Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468473 | 0.83 | CYP1A2 (0.45) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL3379806 | 0.83 | CYP1A2 (0.45) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL1684411 | 0.83 | ALDH1A1 (0.48) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL1464650 | 0.81 | LOXL2 (0.50) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL14744170 | 0.81 | CYP1A2 (0.47) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL30206593 | 0.81 | CYP1A2 (0.47) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL28429346 | 0.80 | KCNJ1 (0.44) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL734091 | 0.79 | CYP1A2 (0.62) | CYP1A2ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL6665984 | 0.79 | TSHR (0.53) | CYP1A2POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL2236124 | 0.79 | CYP1A2 (0.41) | CYP1A2POLBALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104250257-B | 3,4 dihydro 1H benzos [c] [1,2] Evil boric acid compounds or its officinal salt and its production and use | 上海翰森生物医药科技有限公司 | 2017-06-16 | — | — | CN | disclosed |