Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Resorcinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL37801 | 0.93 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Resorcinol SCHEMBL28826037 | 0.93 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Resorcinol SCHEMBL3731090 | 0.92 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Resorcinol SCHEMBL27815945 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Metacresol SCHEMBL28170940 | 0.85 | ACHE (0.55) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Resorcinol SCHEMBL29115764 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL27859351 | 0.84 | CYP3A4 (0.44) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Phenol SCHEMBL3407086 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Resorcinol SCHEMBL28402864 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 | |
| Phenol SCHEMBL28404082 | 0.83 | TDP1 (0.50) | ALDH1A1TSHRCYP3A4SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111420560-B | Preparation method of low-pressure positively-charged nanofiltration membrane, product and application thereof | 贵州省材料产业技术研究院 | 2022-04-12 | — | — | CN | disclosed |
| CN-111420560-A | Preparation method of low-pressure positively-charged nanofiltration membrane, product and application thereof | 贵州省材料产业技术研究院 | 2020-07-17 | — | — | CN | disclosed |