Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014668 | 0.90 | KMT2A (0.39) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL2014085 | 0.86 | KMT2A (0.38) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL2017923 | 0.86 | KMT2A (0.38) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL3495125 | 0.83 | ABCB1 (0.39) | LMNAGAA | |
| SCHEMBL2014768 | 0.78 | LMNA (0.35) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL3494272 | 0.78 | OPRD1 (0.45) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL3493659 | 0.78 | NR1H2 (0.40) | — | |
| SCHEMBL17821462 | 0.76 | KMT2A (0.42) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL3494682 | 0.76 | KMT2A (0.39) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL4899270 | 0.73 | KMT2A (0.56) | KMT2AMEN1CACNA2D1CACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285793-A | Fluorine-substituted bimolecular carbazole derivative, and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | disclosed |