Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429419 | 0.86 | KMT2A (0.40) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL2014668 | 0.84 | KMT2A (0.39) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL2014085 | 0.83 | KMT2A (0.38) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL2014768 | 0.81 | LMNA (0.35) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL3495125 | 0.81 | ABCB1 (0.39) | CCR5HTR2BCYP2D6CYP3A4 | |
| SCHEMBL3494272 | 0.75 | OPRD1 (0.45) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL17821462 | 0.74 | KMT2A (0.42) | KMT2AMEN1SLC6A9CACNA1ACACNA2D1 | |
| SCHEMBL4899270 | 0.70 | KMT2A (0.56) | KMT2AMEN1CACNA2D1CACNB1CACNA1C | |
| SCHEMBL4099589 | 0.69 | SLC6A9 (0.47) | KMT2ASLC6A9CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL4104488 | 0.69 | SLC6A9 (0.47) | KMT2ASLC6A9CACNA1ACACNA2D1CACNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130382-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130382-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | KMT2A 2053/4885MEN1 2826/4885SLC6A9 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.