Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.53 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429593 | 0.86 | PIN1 (0.66) | PIN1RHEBEGLN1HSP90AA1ESR2 | |
| SCHEMBL16268186 | 0.85 | MAPT (0.37) | PIN1MAPTEGLN1CCND3CDK6 | |
| SCHEMBL4811045 | 0.81 | PIN1 (0.54) | PIN1RHEBMAPTAURKAABL1 | |
| SCHEMBL31024214 | 0.79 | PIN1 (0.53) | PIN1RHEBMAPTEGLN1CCND3 | |
| SCHEMBL482085 | 0.79 | PIN1 (0.53) | PIN1RHEBMAPTEGLN1 | |
| SCHEMBL2214853 | 0.79 | PIN1 (0.76) | PIN1RHEBMAPTHSP90AA1ESR2 | |
| SCHEMBL523253 | 0.79 | RHEB (0.54) | PIN1RHEBMAPTLMNAKDR | |
| SCHEMBL4399173 | 0.79 | PIN1 (0.53) | PIN1RHEBMAPTLMNAKDR | |
| SCHEMBL2243699 | 0.79 | PIN1 (0.53) | PIN1RHEBEGLN1LMNATDP1 | |
| SCHEMBL4826512 | 0.79 | EGLN1 (0.53) | PIN1MAPTEGLN1LMNAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111426673-A | Gold and silver hybrid nano-particles and preparation method and application thereof | 南京工业大学 | 2020-07-17 | — | — | CN | claimed |
| CN-111426673-A | Gold and silver hybrid nano-particles and preparation method and application thereof | 南京工业大学 | 2020-07-17 | — | — | CN | disclosed |