Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429591 | 0.86 | PIN1 (0.53) | PIN1HSP90AA1ESR2TDP1EGLN1 | |
| SCHEMBL19129660 | 0.85 | PIN1 (0.51) | PIN1HSP90AA1ESR2TDP1EGLN1 | |
| SCHEMBL17693449 | 0.85 | PIN1 (0.47) | PIN1EGLN1HRH4MPOHRH3 | |
| SCHEMBL4806542 | 0.81 | PIN1 (0.68) | PIN1HSP90AA1ESR2TDP1EGLN1 | |
| SCHEMBL29527229 | 0.79 | PIN1 (0.66) | PIN1TDP1EGLN1RHEBHRH4 | |
| SCHEMBL21063893 | 0.79 | PIN1 (0.66) | PIN1HSP90AA1ESR2TDP1EGLN1 | |
| SCHEMBL523254 | 0.79 | PIN1 (0.66) | PIN1TDP1EGLN1RHEBHRH4 | |
| SCHEMBL4399180 | 0.79 | PIN1 (0.66) | PIN1TDP1SMN1; SMN2APEX1HRH4 | |
| SCHEMBL3644545 | 0.79 | PIN1 (0.66) | PIN1HSP90AA1ESR2TDP1EGLN1 | |
| SCHEMBL2243706 | 0.79 | PIN1 (0.66) | PIN1TDP1EGLN1APEX1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111426673-A | Gold and silver hybrid nano-particles and preparation method and application thereof | 南京工业大学 | 2020-07-17 | — | — | CN | disclosed |