Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268186 | 0.87 | MAPT (0.37) | PIN1CHEK2HRH4EGLN1 | |
| SCHEMBL28429593 | 0.85 | PIN1 (0.66) | PIN1HRH4EGLN1MPOHRH3 | |
| SCHEMBL19129660 | 0.83 | PIN1 (0.51) | PIN1HRH4EGLN1MPOHRH3 | |
| SCHEMBL11211769 | 0.80 | PIN1 (0.73) | PIN1CHEK2HRH4 | |
| SCHEMBL7152026 | 0.80 | HTR3E (0.57) | CHEK2HRH4HRH3 | |
| SCHEMBL28845532 | 0.79 | HSP90AA1 (0.62) | PIN1CHEK2PKN1PKN2EGLN1 | |
| SCHEMBL14690390 | 0.76 | PIN1 (0.76) | PIN1CHEK2PKN1PKN2 | |
| SCHEMBL7153789 | 0.76 | EGLN1 (0.62) | CHEK2EGLN1 | |
| SCHEMBL14690446 | 0.76 | HRH4 (0.60) | CHEK2HRH4EGLN1 | |
| SCHEMBL28918786 | 0.76 | CHEK2 (0.37) | PIN1CHEK2PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442771-B2 | Trans-base tunnel reader for sequencing | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-10-15 | — | — | US | claimed |
| US-10442771-B2 | Trans-base tunnel reader for sequencing | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| US-20170204066-A1 | NANOPORE BASED SEQUENCER | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-07-20 | — | — | US | disclosed |
| US-20160108002-A1 | UNIVERSAL READER MOLECULE FOR RECOGNITION TUNNELING | NATIONAL INSTITUTES OF HEALTH | 2016-04-21 | — | — | US | disclosed |
| US-20160108002-A1 | UNIVERSAL READER MOLECULE FOR RECOGNITION TUNNELING | NATIONAL INSTITUTES OF HEALTH | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108002-A1 | UNIVERSAL READER MOLECULE FOR RECOGNITION TUNNELING | TARS2, MTR, BRD4 | PIN1 274/4885CHEK2 2337/4885PKN1 3293/4885 |
| US-20170204066-A1 | NANOPORE BASED SEQUENCER | DNMT3A, DNTT, TELO2 | PIN1 860/4885CHEK2 2005/4885PKN1 2151/4885 |
| US-10442771-B2 | Trans-base tunnel reader for sequencing | DNTT, TRDMT1, TELO2 | PIN1 467/4885CHEK2 2385/4885PKN1 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.