Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433205 | 0.86 | SMN1; SMN2 (0.70) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6037573 | 0.81 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL26373225 | 0.78 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL28310352 | 0.77 | RAB9A (0.79) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| Quinoline SCHEMBL28309612 | 0.76 | RAB9A (0.67) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL20284308 | 0.76 | RAB9A (0.53) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL13702094 | 0.75 | RAB9A (0.59) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL28071638 | 0.75 | RXFP1 (0.56) | RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL26373245 | 0.74 | SMN1; SMN2 (0.70) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL740617 | 0.74 | MGAM (0.56) | SMN1; SMN2TP53ALDH1A1CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156683-B | Synthesis method of quinoline oxide | 青岛农业大学 | 2020-06-26 | — | — | CN | disclosed |