Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.70 |
| ▸ | RELA | Q04206 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28309612 | 0.89 | RAB9A (0.67) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL28430157 | 0.86 | RAB9A (0.51) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL1131467 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL28310352 | 0.82 | RAB9A (0.79) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL28426782 | 0.80 | GRIK1 (0.55) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL740617 | 0.79 | MGAM (0.56) | SMN1; SMN2POLBCNR2ALDH1A1MAPT | |
| SCHEMBL13201008 | 0.77 | RAB9A (0.70) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL26373245 | 0.77 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5625543 | 0.74 | GRM2 (0.47) | CNR2FAAHPTPN1MAPT | |
| SCHEMBL7862687 | 0.74 | RAB9A (0.70) | SMN1; SMN2RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156683-B | Synthesis method of quinoline oxide | 青岛农业大学 | 2020-06-26 | — | — | CN | disclosed |