Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20832656 | 1.00 | RAB9A (0.45) | RAB9APPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL22623099 | 0.90 | CCRL2 (0.38) | RAB9APPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL30234059 | 0.90 | CCRL2 (0.38) | RAB9APPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL22227986 | 0.90 | PPARG (0.47) | RAB9APPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL22227983 | 0.90 | PPARG (0.47) | RAB9APPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL20832678 | 0.89 | PPARG (0.55) | PPARGNR2E3NCOR2L3MBTL1KMT2A | |
| SCHEMBL20820811 | 0.86 | PPARG (0.43) | PPARGNR2E3NCOR2KMT2AMEN1 | |
| SCHEMBL20820812 | 0.86 | PPARG (0.43) | PPARGNR2E3NCOR2KMT2AMEN1 | |
| SCHEMBL20832804 | 0.83 | L3MBTL1 (0.46) | RAB9APPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL22227915 | 0.83 | L3MBTL1 (0.46) | RAB9APPARGNR2E3NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094255-B | Compounds having cyclic structures | 第一三共株式会社 | 2023-10-03 | — | — | CN | disclosed |
| CN-111094255-A | Compound having cyclic structure | 第一三共株式会社 | 2020-05-01 | — | — | CN | disclosed |