Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021536 | 0.81 | MCL1 (0.60) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 | |
| SCHEMBL1520240 | 0.79 | TBXAS1 (0.64) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 | |
| SCHEMBL28428521 | 0.79 | ALDH1A1 (0.58) | MCL1ALDH1A1KMT2AKDM4EALOX5 | |
| SCHEMBL18180209 | 0.78 | CDC25A (0.63) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 | |
| SCHEMBL12874520 | 0.78 | KMT2A (0.66) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 | |
| SCHEMBL6567317 | 0.77 | ALDH1A1 (0.58) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 | |
| SCHEMBL9701519 | 0.76 | KMT2A (0.60) | ALDH1A1TBXAS1KMT2ASTAT3KDM4E | |
| SCHEMBL16540887 | 0.75 | MCL1 (1.00) | MCL1PTGDR2 | |
| SCHEMBL8690315 | 0.74 | S1PR2 (0.58) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 | |
| SCHEMBL30979650 | 0.73 | ALDH1A1 (0.55) | MCL1ALDH1A1TBXAS1KMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111501-B | Fatty amino acid modified indole ethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2022-04-22 | — | — | CN | claimed |
| CN-109081801-B | Acidic amino acid modified indoloethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | claimed |
| CN-109111390-B | Met-modified indoloethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | claimed |
| CN-109081803-B | Polar amino acid modified indoloethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | claimed |
| CN-109081802-B | Indole ethanol derivative modified by basic amino acid, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | claimed |
| CN-108976159-B | Aromatic amino acid modified indole ethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2020-07-28 | — | — | CN | claimed |
| CN-109111501-B | Fatty amino acid modified indole ethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-109081801-B | Acidic amino acid modified indoloethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109081803-B | Polar amino acid modified indoloethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109111390-B | Met-modified indoloethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109081802-B | Indole ethanol derivative modified by basic amino acid, and synthesis, activity and application thereof | 首都医科大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-108976159-B | Aromatic amino acid modified indole ethanol derivative, and synthesis, activity and application thereof | 首都医科大学 | 2020-07-28 | — | — | CN | disclosed |