Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350654 | 0.97 | CSNK1D (0.43) | CSNK1DALDH1A1GAAPOLBGHSR | |
| SCHEMBL214821 | 0.88 | CSNK1D (0.43) | CSNK1DGAADYRK1AACP1SMN1; SMN2 | |
| SCHEMBL213647 | 0.86 | GHSR (0.41) | CSNK1DALDH1A1GAAPOLBGHSR | |
| SCHEMBL209925 | 0.80 | CSNK1D (0.51) | CSNK1DPOLBGHSRDYRK1AKMT2A | |
| SCHEMBL209978 | 0.79 | CSNK1D (0.49) | CSNK1DDYRK1AACP1 | |
| SCHEMBL210507 | 0.74 | CSNK1D (0.47) | CSNK1DALDH1A1GHSRDYRK1AKMT2A | |
| SCHEMBL2721555 | 0.74 | CSNK1D (0.54) | CSNK1DALDH1A1GHSRDYRK1AACP1 | |
| SCHEMBL4342546 | 0.74 | RAB9A (0.58) | CSNK1DALDH1A1GAADYRK1AKMT2A | |
| SCHEMBL211950 | 0.74 | CSNK1D (0.45) | CSNK1DALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL211695 | 0.74 | NPC1 (0.55) | CSNK1DALDH1A1GAAACP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |