Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.49 |
| ▸ | CASP1 | P29466 | 10/20 | 0.49 |
| ▸ | CASP7 | P55210 | 9/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430136 | 0.80 | CFTR (0.57) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL29388744 | 0.80 | CFTR (0.57) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL29386548 | 0.78 | CFTR (0.55) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL28433786 | 0.78 | CFTR (0.55) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL28736739 | 0.74 | ALDH1A1 (0.65) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL17184347 | 0.72 | CFTR (0.59) | USP2ALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL4659601 | 0.69 | BRD4 (0.50) | ALDH1A1LMNAKMT2ABRD4 | |
| SCHEMBL4311048 | 0.69 | SCD (0.51) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL28430633 | 0.69 | ALDH1A1 (0.45) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL29388772 | 0.69 | ALDH1A1 (0.45) | USP2ALDH1A1CYP1A2CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423388-B | 7-methoxy-3-phenylquinoxaline-2 (1H) -one derivative and preparation method and application thereof | 浙江工业大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-111423388-A | 7-methoxy-3-phenylquinoxaline-2 (1H) -one derivative and preparation method and application thereof | 浙江工业大学 | 2020-07-17 | — | — | CN | disclosed |