Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500298 | 0.88 | HTR4 (0.36) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6586553 | 0.87 | KDM4E (0.41) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL19211613 | 0.86 | KDM4E (0.40) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL30732410 | 0.85 | HTR4 (0.34) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6600592 | 0.85 | HTR4 (0.38) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL19211614 | 0.85 | HTR4 (0.34) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7386673 | 0.80 | HSD17B10 (0.40) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL28922401 | 0.78 | ACVRL1 (0.36) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL19211576 | 0.78 | ACVRL1 (0.34) | ACVRL1 | |
| SCHEMBL8690082 | 0.78 | KDM4E (0.37) | HTR4HTR3AHTR1AADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | disclosed |