⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356075 | 0.98 | — | — | |
| SCHEMBL16581335 | 0.80 | — | — | |
| SCHEMBL11436590 | 0.80 | TSHR (0.30) | — | |
| SCHEMBL394606 | 0.78 | DNM1 (0.40) | — | |
| SCHEMBL8935552 | 0.76 | HTT (0.41) | — | |
| SCHEMBL2563068 | 0.76 | HTT (0.41) | — | |
| SCHEMBL27805552 | 0.76 | HTT (0.41) | — | |
| SCHEMBL9277188 | 0.76 | — | — | |
| SCHEMBL18704189 | 0.76 | HTT (0.41) | — | |
| SCHEMBL27805555 | 0.76 | HTT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270562-A1 | BIS-RNAI COMPOUNDS FOR CNS DELIVERY | BANK OF AMERICA, N.A. | 2025-08-28 | — | — | US | disclosed |
| EP-4367237-A2 | BIS-RNAI COMPOUNDS FOR CNS DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| US-20230257745-A1 | Circular siRNAs | BANK OF AMERICA, N.A. | 2023-08-17 | — | — | US | disclosed |
| WO-2023283403-A2 | BIS-RNAI COMPOUNDS FOR CNS DELIVERY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2022011214-A1 | CIRCULAR SIRNAS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-01-13 | — | — | WO | disclosed |
| CN-113631764-A | Methods, compositions, and apparatus for solid state synthesis of scalable polymers for use in single molecule sequencing | 斯特拉托斯基因公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-106467913-B | Probe inversion method for in situ synthesis of probe arrays | 生捷科技控股公司 | 2021-07-20 | — | — | CN | disclosed |
| US-10695735-B2 | Probe inversion process for in situ synthesized probe arrays | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2020-06-30 | — | — | US | disclosed |
| CN-106460232-B | Oligonucleotide probe inversion method for in situ synthesized probe array | 生捷科技控股公司 | 2019-12-24 | — | — | CN | disclosed |
| US-20190284619-A1 | IN SITU PROBE INVERSION PROCESS FOR CONTSTRUCTING PROBE ARRAYS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2019-09-19 | — | — | US | disclosed |
| US-20160258970-A1 | SMALL MOLECULE-DEPENDENT SPLIT APTAMER LIGATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-09-08 | — | — | US | disclosed |
| EP-3049426-A1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | Centre National De La Recherche Scientifique (FR) | 2016-08-03 | — | — | EP | disclosed |
| US-9279805-B2 | Small molecule-dependent split aptamer ligation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-03-08 | — | — | US | disclosed |
| WO-2015040209-A1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-26 | — | — | WO | disclosed |
| EP-2851371-A1 | Glycoclusters and their pharmaceutical use as antibacterials | Centre National de la Recherche Scientifique (CNRS) (FR) | 2015-03-25 | — | — | EP | disclosed |
| US-20150072352-A1 | SMALL MOLECULE-DEPENDENT SPLIT APTAMER LIGATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-03-12 | — | — | US | disclosed |
| US-8735367-B2 | Small molecule-dependent split aptamer ligation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130164739-A1 | SMALL MOLECULE-DEPENDENT SPLIT APTAMER LIGATION | UNIVERSITY OF UTAH | 2013-06-27 | — | — | US | disclosed |
| US-8268977-B2 | Strongly quenching oligomeric excimer/quencher pairs for detection schemes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100129820-A1 | STRONGLY QUENCHING OLIGOMERIC EXCIMER/QUENCHER PAIRS FOR DETECTION SCHEMES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-05-27 | — | — | US | disclosed |