SCHEMBL18704189

SCHEMBL18704189

CCCCCCCCCCCCCCCCCCOP(N)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
CA1 P00915 8/20 0.40
CA2 P00918 8/20 0.40
CA9 Q16790 7/20 0.40
LPAR3 Q9UBY5 6/20 0.40
LPAR2 Q9HBW0 5/20 0.40
CA12 O43570 3/20 0.40
CA7 P43166 3/20 0.40
CA14 Q9ULX7 3/20 0.40
LPAR1 Q92633 2/20 0.40
CA3 P07451 2/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
NAAA Q02083 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27805555 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL27805552 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL27826191 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL27826184 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL2563068 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL27826190 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL27826182 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL8935552 1.00 HTT (0.41) HTTMEN1THRBKMT2AMAPT
SCHEMBL8668225 0.98
SCHEMBL27826296 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4627082-A1 TREATMENT OF MTRES1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2025-10-08 EP disclosed
US-20250250568-A1 MODIFIED OLIGONUCLEOTIDES EMPIRICO INC (US) 2025-08-07 US disclosed
US-20250188455-A1 LIPOPHILIC OLIGONUCLEOTIDE CONJUGATES VANDERBILT UNIVERSITY 2025-06-12 US disclosed
US-12258563-B2 Modified oligonucleotides EMPIRICO INC. (US) 2025-03-25 US disclosed
WO-2025059326-A1 MODIFIED OLIGONUCLEOTIDES EMPIRICO INC. (US) 2025-03-20 WO disclosed
EP-4499834-A2 MODIFIED OLIGONUCLEOTIDES EMPIRICO INC. (US) 2025-02-05 EP disclosed
CN-119278265-A Modified oligonucleotides 艾姆皮瑞克公司 2025-01-07 CN disclosed
US-20240409938-A1 LIPOPHILIC SIRNA CONJUGATES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES VANDERBILT UNIVERSITY 2024-12-12 US disclosed
US-20240271130-A1 LIPOPHILIC SIRNA CONJUGATES FOR THE TREATMENT OF INFLAMMATORY DISEASES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-15 US disclosed
US-20240264142-A1 MOLECULAR DETECTION AND COUNTING USING NANOPORES ROCHE SEQUENCING SOLUTIONS INC (US) 2024-08-08 US disclosed
EP-3526349-B1 MOLECULAR DETECTION AND COUNTING USING NANOPORES HOFFMANN LA ROCHE (CH) 2021-03-17 EP disclosed
EP-3464310-B1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING HOFFMANN LA ROCHE (CH) 2021-01-27 EP disclosed
US-20200377944-A1 COMPOSITIONS AND METHODS FOR UNIDIRECTIONAL NUCLEIC ACID SEQUENCING ROCHE SEQUENCING SOLUTIONS INC (US) 2020-12-03 US disclosed
US-20200263248-A1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING Roche Sequencing Solutions, Inc. (US) 2020-08-20 US disclosed
US-10655174-B2 Tagged multi-nucleotides useful for nucleic acid sequencing Roche Sequencing Solutions, Inc. (US) 2020-05-19 US disclosed
US-20190250142-A1 MOLECULAR DETECTION AND COUNTING USING NANOPORES Roche Sequencing Solutions, Inc. 2019-08-15 US disclosed
US-20190241952-A1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING ROCHE SEQUENCING SOLUTIONS INC (US) 2019-08-08 US disclosed
US-20170342485-A1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING Roche Sequencing Solutions, Inc. (US) 2017-11-30 US disclosed
US-20170153257-A1 METHODS OF ESTIMATING LOGD OF TAGGED COMBINATORIAL LIBRARY COMPOUNDS DICE MOLECULES SV, LLC 2017-06-01 US disclosed
WO-2017062973-A2 METHODS OF ESTIMATING LOGD OF TAGGED COMBINATORIAL LIBRARY COMPOUNDS DICE MOLECULES SV, LLC (US) 2017-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10655174-B2 Tagged multi-nucleotides useful for nucleic acid sequencing NT5C3B, POLN, RNGTT HTT 1443/4885MEN1 4287/4885THRB 4373/4885
US-12258563-B2 Modified oligonucleotides TRDMT1, NSUN3, PHAX HTT 1274/4885MEN1 4299/4885THRB 3420/4885
US-20190241952-A1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING NT5C3B, POLN, RNGTT HTT 1443/4885MEN1 4287/4885THRB 4373/4885
US-20170153257-A1 METHODS OF ESTIMATING LOGD OF TAGGED COMBINATORIAL LIBRARY COMPOUNDS PLOD3, JUND, MRPL21 HTT 1847/4885MEN1 356/4885THRB 1727/4885
US-20250250568-A1 MODIFIED OLIGONUCLEOTIDES TRDMT1, NSUN3, PHAX HTT 1274/4885MEN1 4299/4885THRB 3420/4885
US-20200263248-A1 TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING NT5C3B, POLN, RNGTT HTT 1443/4885MEN1 4287/4885THRB 4373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.