SCHEMBL28430852

SCHEMBL28430852

CN1C(=O)c2ccc(NO)cc2C1=O

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.65
ALDH1A1 P00352 8/20 0.61
KDM4E B2RXH2 5/20 0.61
HPGD P15428 4/20 0.61
HSD17B10 Q99714 4/20 0.56
POLB P06746 1/20 0.56
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13105701 0.82 APP (0.66) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL4451466 0.80 ALDH1A1 (0.69) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6342924 0.78 ALDH1A1 (0.62) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL7931380 0.76 KDM4E (0.78) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6340203 0.75 APP (0.58) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL15452102 0.75 ALDH1A1 (0.62) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL31054223 0.75 APP (0.68) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1500415 0.74 ALDH1A1 (0.55) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3024023 0.74 APP (0.66) APPALDH1A1KDM4EHPGDHSD17B10
SCHEMBL10678099 0.73 ALDH1A1 (0.52) APPALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111423430-B Fluorescent probe and preparation method thereof 中山大学 2023-10-13 CN disclosed
CN-111423430-A Fluorescent probe and preparation method thereof 中山大学 2020-07-17 CN disclosed