Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054223 | 0.84 | APP (0.68) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL7931380 | 0.82 | KDM4E (0.78) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL15452102 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL28430852 | 0.80 | APP (0.65) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL18132513 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL13105701 | 0.78 | APP (0.66) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL10915866 | 0.77 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL10098929 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4462900 | 0.75 | KDM4E (0.66) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL22983111 | 0.74 | RAB9A (0.62) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |