Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342924 | 0.83 | ALDH1A1 (0.62) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11935277 | 0.80 | APP (0.50) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31180742 | 0.78 | MEN1 (0.62) | APPALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22079537 | 0.77 | PTK2 (0.51) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13105701 | 0.77 | APP (0.66) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6340923 | 0.76 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL28430852 | 0.75 | APP (0.65) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17090278 | 0.74 | GRIA1 (0.46) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13564882 | 0.74 | CNR2 (0.44) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18669090 | 0.74 | APP (0.52) | APPALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | APEH, PAH, ALAD | APP 3478/4885ALDH1A1 61/4885KDM4E 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.