SCHEMBL2843246

SCHEMBL2843246

Cc1cc(C)n([Si](C)(C)C)n1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
GLS O94925 1/20 0.40
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.38
ALOX15 P16050 3/20 0.37
CYP1A2 P05177 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP2C9 P11712 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP2C19 P33261 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906958 0.84 KDM4E (0.45) KDM4EGAATSHRALDH1A1GLA
SCHEMBL7640706 0.84 KDM4E (0.45) KDM4EGAATSHRALDH1A1GLA
SCHEMBL147208 0.67
SCHEMBL4138642 0.67 HTT (0.68) KDM4EGAATSHRALDH1A1HTT
SCHEMBL19927821 0.67 TSHR (0.52) KDM4ETSHRALDH1A1GLAHTT
SCHEMBL3712068 0.67 RAB9A (0.67) KDM4EGAATSHRALDH1A1HTT
SCHEMBL790617 0.65
SCHEMBL22064861 0.65
SCHEMBL9195964 0.65
SCHEMBL8112989 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297368-A1 METHODS FOR ETCHING METAL OXIDE LAYERS EMPLOYING CYCLICAL ETCHING PROCESSES, AND ASSOCIATED METHODS FOR FORMING METAL OXIDE LAYERS ASM IP HOLDING B.V. (NL) 2025-09-25 US claimed
CN-113936994-A Selective deposition of thin film dielectrics using surface termination chemistry 应用材料公司 2022-01-14 CN claimed
CN-107533951-B Selective deposition of thin film dielectrics using surface termination chemistry 应用材料公司 2021-10-26 CN claimed
US-20180199432-A1 Selective Deposition of Thin Film Dielectrics Using Surface Blocking Chemistry APPLIED MATERIALS, INC. 2018-07-12 US claimed
US-9911591-B2 Selective deposition of thin film dielectrics using surface blocking chemistry APPLIED MATERIALS, INC. (US) 2018-03-06 US claimed
US-20160322213-A1 Selective Deposition Of Thin Film Dielectrics Using Surface Blocking Chemistry APPLIED MATERIALS, INC. 2016-11-03 US claimed
US-20250297368-A1 METHODS FOR ETCHING METAL OXIDE LAYERS EMPLOYING CYCLICAL ETCHING PROCESSES, AND ASSOCIATED METHODS FOR FORMING METAL OXIDE LAYERS ASM IP HOLDING B.V. (NL) 2025-09-25 US disclosed
CN-120157717-A Synthesis method of asymmetric metallocene catalyst 中国科学院大连化学物理研究所 2025-06-17 CN disclosed
CN-118878466-A Trifluoro-azole and its preparation method 特里纳普克公司 2024-11-01 CN disclosed
CN-115038692-B Trifluoro-azole and its preparation method 特里纳普克公司 2024-07-16 CN disclosed
CN-112105603-B Sulfonyl diazoles and N- (fluorosulfonyl) oxazoles and methods of making the same 特里纳普克公司 2024-01-30 CN disclosed
US-11542236-B2 Sulfonyldiazoles and N-(fluorosulfonyl)azoles, and methods of making the same TRINAPCO, INC. (US) 2023-01-03 US disclosed
EP-4097089-A1 TRIFLAZOLES AND METHODS OF MAKING THE SAME Trinapco, Inc (US) 2022-12-07 EP disclosed
EP-2233469-B1 Method for coupling halogen-substituted aromatic substances with trialkylsilyl-substituted heteroatom-containing organic compounds ZYLUM BETEILIGUNGSGMBH & CO PATENTE II KG (DE) 2012-07-18 EP disclosed
US-20120142937-A1 METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) 2012-06-07 US disclosed
EP-2233469-A1 Method for coupling halogen-substituted aromatic substances with trialkylsilyl-substituted heteroatom-containing organic compounds Zylum Beteiligungsgesellschaft mbH & Co. Patente II KG (DE) 2010-09-29 EP disclosed
EP-0291212-B1 POLYMERIZATION OF ACRYLIC ESTERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-24 EP disclosed
US-4965366-A REACTING AZOLE, TRISUBSTITUTED SILANE, AND PRIMARY AMINE PPG INDUSTRIES, INC. (US) 1990-10-23 US disclosed
EP-0291212-A1 Polymerization of acrylic esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-17 EP disclosed
US-4771117-A COCATALYST SYSTEM WITH A TETRACOORDIATE SILICONE ORGANIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142937-A1 METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS TYR, ALK, TTL KDM4E 3540/4885GAA 2397/4885TSHR 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.