Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2843246 | 0.84 | KDM4E (0.45) | KDM4EGAATSHRALDH1A1GLA | |
| SCHEMBL6906958 | 0.84 | KDM4E (0.45) | KDM4EGAATSHRALDH1A1GLA | |
| SCHEMBL147208 | 0.67 | — | — | |
| SCHEMBL4138642 | 0.67 | HTT (0.68) | KDM4EGAATSHRALDH1A1HTT | |
| SCHEMBL3712068 | 0.67 | RAB9A (0.67) | KDM4EGAATSHRALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL4336653 | 0.66 | KDM4E (0.64) | KDM4EGAATSHRALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL4336655 | 0.66 | KDM4E (0.64) | KDM4EGAATSHRALDH1A1HTT | |
| SCHEMBL790617 | 0.65 | — | — | |
| SCHEMBL22064861 | 0.65 | — | — | |
| SCHEMBL9195964 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085515-A1 | TRIS(PYRAZOYL) BASED ANIONS | EQUISTAR CHEMICALS, LP (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6391988-B1 | COORDINATION POLYMERIZATION CATALYSTS | EQUISTAR CHEMICALS L.P. | 2002-05-21 | — | — | US | disclosed |